Bioavailability and its assessment.
نویسندگان
چکیده
Bioavailability is a key pharmacokinetic parameter which expresses the proportion of a drug administered by any nonvascular route that gains access to the systemic circulation. Presented in this review are the different approaches to measurement of bioavailability (absolute and relative), including the case in which intravenous administration is impossible. The rate of drug absorption is also discussed with special emphasis on the possible difficulties encountered using C(max) and T(max) or curve fitting to evaluate the rate of drug absorption.
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ورودعنوان ژورنال:
- Journal of veterinary pharmacology and therapeutics
دوره 27 6 شماره
صفحات -
تاریخ انتشار 2004